The increasing recognition of NMN as a supplement to slow down aging stems from numerous scientific research showing that NMN can slow down aging, and by good claims about NMN as a longevity ingredient by properly-recognized researchers, like Professor David Sinclair from Harvard University, Professor Shin-ichiro Imai from Washington University, and quite a few other folks (R,R,R,R,R).
So now you can get NMN supplements everywhere.
Even so, this tremendously increased demand lead also to unscrupulous sellers to give low-purity NMN supplements, or even NMN supplements that do not include NMN.
Challenges with NMN supplements
Some NMN supplements claim to be “high-purity NMN,” whilst they are in fact low-purity NMN. Some NMN supplements even have much less than 80 percent purity.
Also, what the other 20 percent consists of is not known to consumers. It can be just fillers like flour (made use of to minimize the price), or it could be toxic substances designed as a by-item from the NMN production process.
There are even “NMN supplements” that do not contain NMN, but alternatively contain nicotinamide (a B vitamin that appears somewhat like NMN but has complete different effects in the physique), or that contain nicotinamide riboside (NR).
NR is not the similar as NMN. There are many causes to think that NMN is far better than NR. We explain in this blog post why.
Given the really high manufacturing fees of NMN (it is one particular of the most high-priced meals supplements to generate) some NMN supplement sellers adulterate their merchandise to decrease the fees and make extra profit.
How to obtain the best NMN supplement?
So how can you find the ideal NMN supplement? And make certain the supplement is a trustworthy, good excellent one?
You would have to have to pay interest to the following points:
1. The NMN corporation has esteemed scientific advisors
Make confident your NMN supplement is from a firm that has major longevity scientists in its advisory board, and performs with scientific consultants that are well-known in the field of aging.
You can google these researchers to see if they are connected to a university or lab, and check on PubMed how a lot of studies they have published.
That way you can make sure they are active, nicely-respected scientists. We at NOVOS have such top authorities as board members and advisors.
2. Be skeptical of “high-purity” NMN claims
Acquire a higher-purity (containing far more than 99 % NMN) supplement, so not 1 that has been adulterated with other substances.
Having said that, be skeptical of so called “99 % purity” NMN supplements. Usually, the purity is measured subjectively, and not in an absolute way.
Typically, the “purity” is measured by comparing the supplement with other supplements that are significantly less pure. In this way 1 can claim incredibly high “purities”.
On the other hand, to decide the actual purity, 1 needs to calculate the purity in an objective manner, by measuring the absolute purity of the supplement itself.
Or, when measuring nmn 護膚 by comparing NMN with a gold regular of NMN, the brand’s purity ought to be much more than 100 percent pure (e.g. 101 percent purity). This means the NMN is more pure than the gold standard.
3. Make confident it’s stable, new-generation NMN
Did you know that not al NMN is the exact same?
Newer generation NMN is more steady. NMN is a fragile molecule that when exposed to water molecules can get converted into nicotinamide (NAM).
The stability of NMN is largely determined by the surrounding water molecules, and the organization of the NMN with other surrounding NMN molecules. The water molecules are polar (having various electric charges on unique sides), which can influence the electron configuration of the NMN molecule and lead to much less stability.
NMN molecules that are far more orderly organized and more compactly arranged endure significantly less from the destabilizing interaction with water molecules each in the solution and with water from air. Furthermore, producing extra “high-density” NMN by decreasing water content improves stability.
We at NOVOS present this sort of next-generation, much more stable NMN.
The NMN in NOVOS Boost arranges itself into spherical crystals (as opposed to sawtooth crystals), which are extra capable of blocking contact with humidity in the air, which increases the stability and shelf life of our NMN. Compared to sawtooth crystal shapes, the spherical crystal is more ordered, compact and therefore every single NMN molecule will have much less exposure to air and water.
There exists even far more crystalline NMN (and NMN derivatives), which requires specific organization of the NMN molecules, for which David Sinclair’s firm MetroBiotech has filed patents. See for example this patent. Nonetheless, this is probably overkill.
four. Third party-lab testing of NMN
Make sure NMN supplement seller has worked with each other with third party labs that checked the supplement for contaminants such as:
Heavy metals (e.g. lead, arsenic, cadmium and mercury)
Bacteria (e.g. E coli, S aureus, Salmonella)
Yeast and mold
Toxins (e.g. toluene, xylenes, trichloroethylene, isopropyl alcohol, ethylene oxide, ethyl ether, acetone, benzene, chloroform, acetonitrile, etc). Toluene is an vital contaminant that needs to checked.
Be conscious, some firms only test heavy metals, but not microorganisms like yeast and bacteria, or only test for microorganisms and not for heavy metals.
Make certain your NMN supplement has been third-party tested by independent testing services to confirm purity and safety. Numerous sellers of NMN supplements use significantly less well-known and significantly less reputed testing businesses.
five. The NMN is appropriately manufactured
Make positive your NMN supplement is created in a facility that performs according to GMP (Great Manufacturing Practices) and to the most current ISO norms.
Also, the production approach of NMN needs to be state-of-the-art.
This indicates for example that the pH and water content material in the course of the production method have to be really well controlled. A too acid or also alkaline atmosphere will break the electric balance of the NMN crystals. NOVOS Increase NMN is pH balanced, which improves the internal structure and stability of the crystals through production. Further, the water content in the crystals is controlled through production, which additional improves the NMN’s stability.
It’s important to use in this process novel-generation NMN produced of spherical crystals, which has larger bulk density and fluidity, avoiding unstable dosages due to raising dust in the production course of action.
Why NOVOS’ NMN is various
NOVOS Enhance is a exceptional NMN supplement adhering to all of the above.
We use rigorous science, work collectively with the top scientific professionals in the aging field, do due diligence and conduct trustworthy in depth testing to make sure you have the very best high-excellent NMN supplement, which pairs excellently with our foundational formulation, NOVOS Core.
Also, our NMN is subsequent-generation NMN that is a lot more steady.
NOVOS’ NMN is third-party tested, higher-purity NMN. Our NMN is likely the most thoroughly tested NMN on the industry: We test for far far more contaminants than lots of other organizations do.